First, we have to understand the difference between bigger and smaller. The big things always may not be mightier. Rather it is valued by those who can think deeper, that is the minuets form of matter and energy, and the subliminal currents of conscious force are exponentially more powerful than their gross manifestation. For example 500 grams of gold cannot do what an atom of its negligible particle does. All activities of this material world are governed by this rule. This atomic energy of the drug is given maximum importance not only in Homeopathy.